The Lab

• Five thousand square foot lab containing liquid handling robotic equipment for plate preparation and assays.
• Instrumentation for cell-based and biochemical assays using absorbance, fluorescence polarization, time resolved fluorescence and luminescence, and radioactive endpoints.
• TekCel TubeStore compound management system for long term compound storage in an inert environment.
• Unique screening library containing 100,000 diverse compounds.  We have purchased compounds from Chemical Diversity Labs, Chembridge, Maybridge and Tripos.
• Special 10,000 diversity subset also available for screening.

Strategic Partners

• Core Technology Alliance (www.ctaalliance.org) - The CTA is a collaborative network of advanced technology service facilities located at major research institutions across Michigan. These fee-for-service laboratories conduct biomedical research in the areas of genomics, proteomics, structural biology, animal models, bioinformatics, bio-imaging, and antibody technology.

• Kalexsyn (www.kalexsyn.com) - Kalexsyn provides medicinal chemistry services to scientific customers engaged in the drug discovery process. Kalexsyn offers expertise in all aspects of medicinal chemistry, including organic synthesis, physical property modification, analog strategies, and diversification of compound collections. Their services can accelerate a client's drug discovery program at all stages, including early SAR studies of screening hits, optimization of leads and synthesis of intermediates and building blocks.

• PharmOptima (www.pharmoptima.com) - PharmOptima provides clients with multidisciplinary input to solve research and development issues, including providing consultation and laboratory support for target selection and HTS assays. PharmOptima's scientists have a successful research and development track record in cardiovascular, central nervous system, cancer, dermatology, and infectious diseases.

• Proteos (www.proteos.net) - Proteos provides expertise in three areas of protein science:
  • Custom Services in Protein Expression and Production
  • Protein Products
  • Translational Research for Commercialization
  Proteos applies a battery of analytical procedures to assure the quality of its products, including protein sequencing and mass spectroscopy. They also aid in assay development and application of given protocols as part of quality assurance.

• Global Lifescience Solutions, LLC (www.globallifesciencesolutions.com) - A life sciences contract research and consulting firm offering integrated technical services for companies focused on product innovation in the fields of pharmaceuticals, biotechnology, dietary supplements, food and nanotechnology. High Content Screening is just one of the many services GLS provides.
  

Click here for a complete MHTSC brochure.